Bespoke peptide synthesis scoped against your specification, with analytical release criteria and a documentation package agreed before synthesis begins.
Custom synthesis is the route for sequences that are not carried as catalogue references, or for a catalogue sequence required at a specification, quantity or documentation standard that differs from the standard listing. The workflow below describes how a requirement becomes a delivered batch.
Target sequence, modifications, labelling requirements and anticipated difficulty are reviewed before a feasibility position is given.
Purity target, quantity, salt form, counter-ion, packaging format and release criteria are fixed in the written quotation.
Solid-phase or flow-assisted assembly with in-process checks appropriate to the sequence length and modification set.
Preparative reverse-phase chromatography to the agreed purity target, with re-purification where the first pass does not meet specification.
Identity by mass spectrometry and purity by HPLC against the agreed criteria, followed by documentation assembly and review.
Non-disclosure terms can be agreed before sequence disclosure, and no customer sequence or project detail is published or reused.
| Typical sequence range | 5–60 residues (longer sequences reviewed individually) |
|---|---|
| Modifications supported | Acetylation, amidation, acylation, PEGylation, cyclisation, D-amino acid substitution, fluorescent labelling |
| Purity options | Crude, 95%+, 98%+, 99%+ (RP-HPLC, area %) |
| Scale | Milligram to multi-gram; larger quantities reviewed per project |
| Release documentation | Certificate of Analysis, HPLC chromatogram, mass spectrum, batch traceability record |
| Documentation format | Adaptable to institutional template at quotation stage |
| Lead time | Stated per project after sequence review |
Bulk-grade input material quoted per project, with specification, analytical release criteria and packaging ag…
Identity and purity determination against agreed criteria, with documentation assembled to the format your rev…
Condition-appropriate packaging matched to the material specification and destination, with the regime recorde…
Quotations, supplier files, framework terms and documentation formats prepared so that internal review can pro…
Send the catalogue reference or target sequence, required purity, quantity and destination. The procurement desk returns a formal quotation with the documentation package and lead time.